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Key Research Developments Shaping Clinical Practice in Integrative Medicine 2025

A Year in Review

In Dr. Marsden’s Year in Review: Key Research Developments Shaping Clinical Practice in 2025, I synthesize the most important advances shaping integrative and preventive medicine over the past year. Drawing from high-impact, peer-reviewed research published in 2025, this review reflects a clear shift toward precision, personalization, and systems-based care—moving beyond one-size-fits-all approaches and toward more biologically informed, patient-centered clinical strategies .


Throughout the document, I explore key developments in hormone replacement therapy, gut–brain–endocrine interactions, physical activity as a therapeutic intervention in oncology, and emerging evidence for treatments targeting complex chronic conditions such as long COVID. Rather than presenting isolated study findings, I focus on translating mechanistic insights and clinical trial data into practical frameworks that clinicians can apply in real-world settings, with an emphasis on risk stratification, biomarker-guided care, lifestyle co-therapies, and shared decision-making .


This downloadable review is intended to serve as both a clinical reference and a strategic roadmap. My goal is to support clinicians who want to stay aligned with the evolving evidence base while navigating regulatory changes, increasing patient complexity, and the need for long-term health optimization. If you’re looking for a clear, grounded perspective on how the 2025 research landscape should inform modern integrative practice, I invite you to download the full review .


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